Clinical Trials
Current Trials
Our retina specialists and fellows are involved in many clinical trials to continue advancing technology and techniques related to this area of medicine
Pavilion GR41675 – Genentech - Roche [Enrollment Closed]
A Phase III, Multicenter, Randomized study of the efficacy, safety, and pharmacokinetics of the Port Delivery System with Ranizumab in patients with Diabetic Retinopathy
Rhone-X GR41987 – Genentech - Roche [Enrollment Closed]
A Multicenter, open-Label extension study to evaluate the long-term safety and tolerability of Faricimab in patients with Diabetic Macular Edema.
Gather2 ISEE2008 – Iveric Bio [Enrollment Closed]
A Phase 3, multicenter, randomized, double-masked shamcontrolled clinical trial to assess the safety and efficacy of intravitreal administration of Zimura (complement C5 inhibitor) in patients with Geographic Atrophy secondary to Age-Related Macular Degeneration
Condor: CRTH258D2301 – Novartis [Enrollment Closed]
Novartis pharmaceuticals trail entitled: A 96-week, two-arm, randomized single-masked, multi-center, Phase III study assessing the efficacy and safety of Brolucizumab 6mg compared to Panretinal Photocoagulation Laser in patients with Proliferative Diabetic Retinopathy.
Balaton – GR41984 - Genentech - Roche [Enrollment Closed]
A Phase III, Multicenter, Randomized, Double-Masked, Active comparator - controlled study to evaluate the efficacy and safety of Faricimab in patients with Macular Edema secondary to Branch Retinal Vein Occlusion
Comino- GR41986 – Genentech - Roche [Enrollment Closed]
A Phase III, Multicenter, Randomized, Double-Masked, Active comparator controlled study to evaluate the efficacy and safety of Faricimab in patients with Macular Edema secondary to Central Retinal or Hemiretinal Vein Occlusion.
Upcoming Trials - Coming Soon...


Recently Completed Trials
YOSEMITE - GR40349- Genentech Roche
A Phase III, multicenter, randomized, double-masked, active comparator controlled study to evaluate the efficacy and safety of RO6867461 in patients with diabetic macular edema.
TENAYA - GR40306 - Genentech Roche
A Phase III, multicenter, randomized, double-masked, active comparator controlled study to evaluate the efficacy and safety faricimab in patients with neovascular age-related macular degeneration.
COOL-3 - RecensMedical Inc
A Randomized, Masked, Controlled Trial Studying the Use of Rapid Cooling Anesthesia for Local Anesthesia among Patients Receiving Intravitreal Injections.
SCORE2 - NIH (National Eye Institute) 2014 – 2016
Study of Comparative Treatments for Retinal Vein Occlusion 2 [SCORE2]: a multicenter, prospective, randomized non-inferiority trial of eyes with macular edema secondary to central retinal vein occlusion, comparing intravitreal bevacizumab every 4 weeks with intravitreal aflibercept every 4 weeks. 2014-2016
Other Completed Trials
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Diabetic Retinopathy in HIV Subjects Treated with EGRIFTA
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Treatment for center-involved DME in Eyes with Very Good Visual Acuity
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Short-term Evaluation of Combination Corticosteroid + Anti-VEGF Treatment for Persistent Central-involved Diabetic Macular Edema Following Anti-VEGF Therapy in Pseudophakic Eyes
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Lucentis – Avastin Trial Design
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Protocol “L”: Evaluation of Visual Acuity Measurements in Eyes with Diabetic Macular Edema
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Protocol “N”: An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage due to Proliferative Diabetic Retinopathy
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Mild Macular Grid (MMG) for Diabetic Macular Edema
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Steroid Injection for Diabetic Macular Edema
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Vitrectomy for Diabetic Macular Edema
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Peribulbar Triamcinolone
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PRP for Diabetic Macular Edema
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Subclinical Diabetic Macular Edema
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Anecortave Acetate for Wet AMD
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Anecortave Acetate for Dry AMD
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Surgical Therapeutics for Epiretinal Membranes and Vitrectomy
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Branch Vein Occlusion Sheathotomy Study
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Vit 100 (VitrenAse) Study for PVR
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Oral treatment of Diabetic Retinopathy (Lilly)
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Photodynamic Therapy (PDT) Study – Approved by FDA 4/2000
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Macular Translocation for CNV
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Perfluoron (PFO) Phase IV Clinical Trial
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Submacular Surgery Pilot Trials (SST)
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Perfluoron Study (PFO)
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Syntex Ganciclovir Implant Trials
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ISIS CMV Retinitis Trials
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RPE Transplantation Study
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Collaborative Ocular Melanoma
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COMS
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Macular Photocoagulation Study (MPS)
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IOP Vitrectomy Study
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Age-Related Eye Disease Study
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Richard-James Silicone Oil Study
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Vitrectomy for Macular Hole Study
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Endophthalmitis Vitrectomy Study (EVS)
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Advanced ROP Study
