Clinical Trials

 

Current Trials

Our retina specialists and fellows are involved in many clinical trials to continue advancing technology and techniques related to this area of medicine 

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Pavilion GR41675 – Genentech - Roche [Enrollment Closed]

A Phase III, Multicenter, Randomized study of the efficacy, safety, and pharmacokinetics of the Port Delivery System with Ranizumab in patients with Diabetic Retinopathy

 

Rhone-X GR41987 – Genentech - Roche [Enrollment Closed]

A Multicenter, open-Label extension study to evaluate the long-term safety and tolerability of Faricimab in patients with Diabetic Macular Edema.

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Gather2 ISEE2008 –  Iveric Bio [Enrollment Closed]

A Phase 3, multicenter, randomized, double-masked shamcontrolled clinical trial to assess the safety and efficacy of intravitreal administration of Zimura (complement C5 inhibitor) in patients with Geographic Atrophy secondary to Age-Related Macular Degeneration

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Condor: CRTH258D2301 – Novartis [Enrollment Closed]

Novartis pharmaceuticals trail entitled: A 96-week, two-arm, randomized single-masked, multi-center, Phase III study assessing the efficacy and safety of Brolucizumab 6mg compared to Panretinal Photocoagulation Laser in patients with Proliferative Diabetic Retinopathy.

 

Balaton – GR41984 - Genentech - Roche [Enrollment Closed]

A Phase III, Multicenter, Randomized, Double-Masked, Active comparator - controlled study to evaluate the efficacy and safety of Faricimab in patients with Macular Edema secondary to Branch Retinal Vein Occlusion 

 

Comino- GR41986  – Genentech - Roche [Enrollment Closed]

A Phase III, Multicenter, Randomized, Double-Masked, Active comparator controlled study to evaluate the efficacy and safety of Faricimab in patients with Macular Edema secondary to Central Retinal or Hemiretinal Vein Occlusion. 

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Upcoming Trials - Coming Soon...

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Scientist on Computer
Eye Test

Recently Completed Trials

YOSEMITE - GR40349- Genentech Roche

A Phase III, multicenter, randomized, double-masked, active comparator controlled study to evaluate the efficacy and safety of RO6867461 in patients with diabetic macular edema.

 

TENAYA - GR40306 - Genentech Roche 

A Phase III, multicenter, randomized, double-masked, active comparator controlled study to evaluate the efficacy and safety faricimab in patients with neovascular age-related macular degeneration. 

  

COOL-3 - RecensMedical Inc 

A Randomized, Masked, Controlled Trial Studying the Use of Rapid Cooling Anesthesia for Local Anesthesia among Patients Receiving Intravitreal Injections.  

 

SCORE2 - NIH (National Eye Institute)     2014 – 2016

 Study of Comparative Treatments for Retinal Vein Occlusion 2 [SCORE2]: a multicenter, prospective, randomized non-inferiority trial of eyes with macular edema secondary to central retinal vein occlusion, comparing intravitreal bevacizumab every 4 weeks with intravitreal aflibercept every 4 weeks. 2014-2016

Other Completed Trials

  • Diabetic Retinopathy in HIV Subjects Treated with EGRIFTA

  • Treatment for center-involved DME in Eyes with Very Good Visual Acuity

  • Short-term Evaluation of Combination Corticosteroid + Anti-VEGF Treatment for Persistent Central-involved Diabetic Macular Edema Following Anti-VEGF Therapy in Pseudophakic Eyes

  • Lucentis – Avastin Trial Design

  • Protocol “L”: Evaluation of Visual Acuity Measurements in Eyes with Diabetic Macular Edema

  • Protocol “N”: An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage due to Proliferative Diabetic Retinopathy

  • Mild Macular Grid (MMG) for Diabetic Macular Edema

  • Steroid Injection for Diabetic Macular Edema

  • Vitrectomy for Diabetic Macular Edema

  • Peribulbar Triamcinolone

  • PRP for Diabetic Macular Edema

  • Subclinical Diabetic Macular Edema

  • Anecortave Acetate for Wet AMD

  • Anecortave Acetate for Dry AMD

  • Surgical Therapeutics for Epiretinal Membranes and Vitrectomy

  • Branch Vein Occlusion Sheathotomy Study

  • Vit 100 (VitrenAse) Study for PVR

  • Oral treatment of Diabetic Retinopathy (Lilly)

  • Photodynamic Therapy (PDT) Study – Approved by FDA 4/2000

  • Macular Translocation for CNV

  • Perfluoron (PFO) Phase IV Clinical Trial

  • Submacular Surgery Pilot Trials (SST)

  • Perfluoron Study (PFO)

  • Syntex Ganciclovir Implant Trials

  • ISIS CMV Retinitis Trials

  • RPE Transplantation Study

  • Collaborative Ocular Melanoma

  • COMS

  • Macular Photocoagulation Study (MPS)

  • IOP Vitrectomy Study

  • Age-Related Eye Disease Study

  • Richard-James Silicone Oil Study

  • Vitrectomy for Macular Hole Study

  • Endophthalmitis Vitrectomy Study (EVS)

  • Advanced ROP Study

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