RVT Current and Past Study Participation

Ongoing Studies

Comparison of Age-related Macular Degeneration Treatment Trials (CATT): National Eye Institute
The CATT has been organized by the NEI to directly compare two anti-VEGF medications Avastin and Lucentis. These medications act to block the action of Vascular Endothelial Growth Factor (VEGF) which stimulates the growth and leakage of subretinal membranes in AMD. Members of RVT have no ties to the manufacturer of both medications. This study began in February 2008 and is recruiting patients.

Diabetic Retinopathy Clinical Research Network Studies
Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema Study
This clinical trial is designed to compare several treatments for diabetic macular edema. Patients are randomized to standard laser treatment, laser plus intravitreal Ranibizumab, intravitreal Ranibizumab plus deferred laser, or intravitreal triamcinolone plus focal photocoagulation.
Laser-Ranibizumab-Triamcinolone for Proliferative Diabetic Retinopathy (PDR) Study
This study is designed to determine whether the intravitreal injection of Ranibizumab or steroid can reduce the risk of visual acuity impairment with panretinal photocoagulation and increase the chances of at least short term visual acuity improvement in eyes with center-involved macular edema that are undergoing laser for PDR

SCORE
1. Branch Retinal Vein Occlusion
2. Central Retinal Vein Occlusion
The SCORE trials are organized to test the use of intraocular steroids in the treatment of Branch and Central Vein Occlusions.

Allergan Uveitis Study
To determine the safety and efficacy of the applicator systems of 700 mcg compared to 350 mcg of Dexamethoasone DEX PD DDS and a sham injection in the treatment of non-infectious ocular inflammation of the posterior segment in patients with intermediate or posterior Uveitis.

Completed Studies

DRCRnet Studies (National Eye Institute) completed recruitment
Mild Macular Grid (MMG) for Diabetic Macular Edema
Steroid Injection for Diabetic Macular Edema
Vitrectomy for Diabetic Macular Edema
Peribulbar Triamcinolone
PRP for Diabetic Macular Edema
Subclinical Diabetic Macular Edema

Anecortave Acetate for Wet AMD (Alcon Labs)

Anecortave Acetate for Dry AMD (Alcon Labs)

Surgical Therapeutics for Epiretinal Membranes and Vitrectomy (Alcon Labs 2007)

Branch Vein Occlusion Sheathotomy Study

Vit 100 (VitrenAse) Study for PVR

Oral treatment of Diabetic Retinopathy (Lilly)

Photodynamic Therapy (PDT) Study-Approved by FDA 4/2000

Macular Translocation for CNV

Perfluoron (PFO) Phase IV Clinical Trial

Submacular Surgery Pilot Trials (SST)

Diabetic Macular Edema Studies

Perfluoron Study (PFO)

Syntex Ganciclovir Implant Trials

ISIS CMV Retinitis Trials

RPE Transplantation Study

Collaborative Ocular Melanoma

Study (COMS)

Macular Photocoagulation Study (MPS)

IOP Vitrectomy Study

Age-Related Eye Disease Study

Richard-James Silicone Oil Study

Vitrectomy for Macular Hole Study

Endophthalmitis Vitrectomy Study (EVS)

Advanced ROP Study

For Information on any of these studies contact:

Pam Miller, COT
RVT Research Coordinator
Phone: 713-799-1905
Fax: 713-799-1437
Toll Free: 1-800-9RETINA
Email: PamM@RetinaTexas.com

Disclaimer Stuff: The opinions expressed in this website are those of RVT. Diagnosis and therapy should be based on a thorough examination by and recommendations of a qualified eye provider.